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・ Lithocarpus edulis
・ Lithocarpus erythrocarpus
・ Lithocarpus formosanus
・ Lithocarpus glaber
・ Lithocarpus hendersonianus
・ Lithocarpus indutus
・ Lithocarpus kingianus
・ Lithocarpus kingii
・ Lithocarpus kostermansii
・ Lithocarpus kunstleri
・ Lithocarpus maingayi
・ Lithocarpus neorobinsonii
・ Lithocarpus ovalis
・ Lithocarpus platycarpus
・ Lithocholate 6beta-hydroxylase
Lithocholic acid
・ Lithococcus
・ Lithocolletinae
・ Lithoconus
・ Lithocupes
・ Lithodes
・ Lithodes galapagensis
・ Lithodes maja
・ Lithodes santolla
・ Lithodora
・ Lithodora diffusa
・ Lithodora fruticosa
・ Lithodora nitida
・ Lithodora oleifolia
・ Lithodoras dorsalis


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Lithocholic acid : ウィキペディア英語版
Lithocholic acid

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Lithocholic acid, also known as 3α-hydroxy-5β-cholan-24-oic acid or LCA, is a bile acid that acts as a detergent to solubilize fats for absorption. Bacterial action in the colon produces LCA from chenodeoxycholic acid by reduction of the hydroxyl functional group at carbon-7 in the "B" ring of the steroid framework.
It has been implicated in human and experimental animal carcinogenesis. Preliminary ''in vitro'' research suggests that LCA selectively kills neuroblastoma cells, while sparing normal neuronal cells and is cytotoxic to numerous other malignant cell types at physiologically relevant concentrations.
Dietary fiber can bind to lithocholic acid and aid in its excretion in stool; as such, fiber can protect against colon cancer.
LCA (and LCA acetate and LCA propionate) can activate the vitamin D receptor without raising calcium levels as much as vitamin D itself.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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